Brand-new class of antibiotics might do WHAT?

Could it be possible that the mainstream medical community is actually starting to pay attention to gut health?

I was simply shocked when I read about this new antibiotic that uses a brand-new mechanism that directly tackles those tough-to-treat infections… without touching beneficial microbes.

Like, WOW!

Is this too good to be true?

Fine-tuning the details

Folks, this couldn’t come soon enough.

There are many bacteria that have figured out how to avoid antibiotics. Yet, we haven’t developed a new drug to tackle the rising threat of antibiotic resistance. Nor have we figured out how to spare our gut microbiome in doing so.

See, the antibiotics we currently have use a clear-cut tactic… they aim to wipe out everything and anything in the gut. And that includes the good guys that help us stay healthy. But clearly, we’ve missed the mark.

Could this be the tip of the iceberg?

The new drug is designed to tackle a certain type of bacterium known as Gram-negative. These awful bugs cause debilitating, sometimes even fatal infections—like gastroenteritis, urinary tract infections, pneumonia, sepsis, and cholera.

And the antibiotics used to treat these infections are much outdated. In fact, we haven’t seen a drug development since 1968.

But in preliminary trials on mice, a new drug was successfully able to target and eliminate the pathogen, without wiping out the entire gut microbiome.

Not only that, but the mice were able to fight off a secondary infection with C. difficile—a leading cause of dangerous, sometimes fatal infections, especially in hospital settings. (This was not observed in mice treated with routine antibiotics.)

The horizon is hopeful

There are a few new classes of antibiotic drugs currently in preclinical trials.

Both lolamicin and darobactin target Gram-negative bugs, as described above. Plus, the goal for another drug, called teixobactin, is to target Gram-positive bugs, while staying immune to drug resistance.

I don’t usually get excited about antibiotics. But they are needed (and life-saving) in certain situations. Plus, this is a bright example of how science is advancing, which is always exciting.

Of course, it could be more than a decade before these drugs get approved by the U.S. Food and Drug Administration (FDA). But I’m hopeful at this point. And I’m eager to follow the research.

In the meantime, nourishing and protecting your gut will always help keep you healthy. I wrote about a full gut microbiome makeover in back-to-back issues in the March and April 2019 issues of Logical Health Alternatives.

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Source:

“New Era? ‘Double Selective’ Antibiotic Spares the Microbiome.” Medscape, 06/07/2024. (medscape.com/viewarticle/new-era-double-selective-antibiotic-spares-microbiome-2024a1000apx)