Cutting-edge research uncovers the hidden culprit behind stubborn, aching joints

Carrying excess pounds can put incredible strain on your joints. Particularly if they’ve already suffered decades of everyday wear and tear.

Of course, you already know that.

But here’s something you probably don’t know. While extra weight does put added pressure on your joints, some groundbreaking new research shows there’s also another key factor involved in joint pain…

And it’s one you can address right now.

That’s right. You can actually start to relieve your aching joints — even before you reach your target weight. And it all has to do with managing a substance in your body called leptin.

Researchers have discovered that fat cells produce a hormone called leptin. Simply put, leptin is your body’s natural way of managing your weight if you occasionally overeat. Which sounds like a good thing.

Unfortunately, researchers have discovered that a high body mass index (BMI) can actually trigger leptin resistance. This means your brain stops responding to all that extra leptin. So it doesn’t send the signal to shut down appetite.

And you just keep eating — producing more fat and more leptin as a result.

In fact, research shows that people with elevated BMIs can actually have sky-high levels of leptin. In a study done shortly after leptin was discovered two decades ago, researchers measured levels of the hormone in 136 normal-weight people and 139 obese people. They discovered that the obese people had, on average, a whopping 4.2 times as much leptin in their blood than the normal-weight people.

So what does this have to do with your joints? Well, there’s a growing body of evidence linking high levels of leptin with some devastating effects.

For instance, new reports from journals like International Orthopaedics, Life Sciences, and Rheumatology all confirm that too much leptin can cause:

  • Weak cartilage that doesn’t cushion your joints like it’s supposed to
  • More aches, pains, and discomfort that make it hard to bounce back after a long day on your feet
  • Inflammation that keeps your body’s natural defenses in overdrive. (Of course, inflammation is a normal, natural body response. But when it gets out of hand, it can lead to problems.)

What’s worse, research has revealed that 4 out of 5 people with joint pain have excess levels of leptin — or as I call it, “leptin overload” — in their joints. 

So, in essence, being overweight can harm your joints in two different ways. Excess pounds literally put pressure on your hips, knees, and ankles. And they ramp up your body’s production of leptin — which sets off the domino-effect that eventually leads to joint troubles.

But now for the good news. There is a way to put an end to his vicious cycle once and for all. It’s called OralVisc. And it’s a safe, natural, breakthrough with a whole lot of science in its corner.

OralVisc was developed by the same team of scientists who made one of the most important joint health discoveries in history — the first-ever naturally extracted form of hyaluronic acid, a powerful lubricating compound.

That discovery revolutionized the way we think about “cushioning” the joints…and changed the supplement world forever.

So when I heard they’d uncovered an even bigger breakthrough, I met with them personally to get a firsthand look at their work.

They told me that hyaluronic acid is just one member of a family of nutrients called GAGs (glycosaminoglycans). And they’ve been tirelessly analyzing different combinations of GAGs in an attempt to find one that could address leptin overload.

But every time they changed the combination, they got wildly different results.

In fact, one little change could render the whole thing worthless. So they tested and retested for 3 YEARS until finally they hit on the perfect GAG combination — in the exact ratio you need — to conquer leptin overload.

They named it OralVisc, and this breakthrough combination is the only nutrient complex that’s been clinically tested and shown to defeat leptin overload.

This is important because, as I mentioned earlier, research shows that increased leptin levels in your body may actually reduce the thickness of cartilage. And that can contribute to joint pain.

But OralVisc can do much more than just decrease friction in joints.

Researchers gathered 40 men and women who had had knee pain for at least 10 months. The average age of the participants was 61, and they had an average BMI of 35 (a BMI of 18.5 to 25 is considered normal weight).

The researchers divided the participants into two groups. For three months, one group took 80 mg a day of OralVisc, and one group took a placebo.

At the end of the study, the OralVisc group scored significantly better on joint pain tests. The average pain score of the OralVisc group dropped from 40.3 at the beginning of the study to 27.6 at the end. But the placebo group’s score stayed almost the same: from 40.5 to 39.6.

The OralVisc group also had reduced inflammatory markers in their blood and synovial fluid. And they had lower levels of bradykinin, a substance in the joints that starts the inflammation process and stimulates pain receptors. (And remember, some inflammation is perfectly fine. You just want to make sure it stays within normal ranges.)

Even more impressive, the leptin levels in synovial fluid dropped 24 percent in the OralVisc group. But they actually increased 3 percent in the placebo group.

And if that weren’t enough, the OralVisc group also had 19 percent lower triglyceride levels than the placebo group.

You can see why I’m so excited about OralVisc. It’s the only joint supplement that targets leptin. And based on the research, leptin may very well be the hidden culprit behind aching joints in the vast majority of people.

Which means that OralVisc could provide the relief you just haven’t been able to get from other natural joint formulas.

OralVisc is so new, it’s not widely available yet. But you can find it as the featured ingredient of my MetaJoint Advanced formula.

If you’ve been looking for something to soothe stubborn, aching joints to no avail, this could be the supplement you’ve been waiting for — so I encourage you to try it today.

And be sure to keep me posted on your results (you can send emails to feedback@drpescatore.com). So far the response has been terrific! I can’t wait for even more success stories to start rolling in.

Sources:

“Serum immunoreactive-leptin concentrations in normal-weight and obese humans.”N Engl J Med. 1996 Feb 1;334(5):292-5.

“Cross-sectional and longitudinal associations between circulating leptin and knee cartilage thickness in older adults.”Ann Rheum Dis. 2015 Jan;74(1):82-8.

“Towards a pro-inflammatory and immunomodulatory emerging role of leptin.” Rheumatology 2006;45:944–950.

“Cross-sectional and longitudinal associations between circulating leptin and knee cartilage thickness in older adults.”Ann Rheum Dis. 2015 Jan;74(1):82-8.

“The effects of an oral preparation containing hyaluronic acid (Oralvisc®)
on obese knee osteoarthritis patients determined by pain, function, bradykinin, leptin, inflammatory cytokines, and heavy water analyses.” Rheumatol Int. 2015 Jan;35(1):43-52


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