An old favorite emerges as a new Alzheimer’s breakthrough

If you’ve been reading Logical Health Alternatives for a while, you might have noticed that resveratrol didn’t get a spot on my annual Desert Island supplement list this year. Not because it isn’t a critically important supplement. (It definitely still is.) But because research on its benefits has slowed down considerably over the last several years.

That’s why I’m thrilled to tell you about some exciting resveratrol news today. Especially since it may offer new hope to patients facing Alzheimer’s disease.

Researchers at Georgetown Medical University presented these findings at the Alzheimer’s Association International Conference 2016 in Toronto this past summer. Their recent work expanded on previous clinical research on Alzheimer’s patients.

This time, they analyzed the cerebrospinal fluid of 38 subjects with Alzheimer’s—half of whom supplemented with resveratrol daily for a year, the other half of whom received a placebo.

Sample results showed that the patients taking resveratrol benefited from a 50 percent reduction in a compound called matrix metalloproteinase-9 (MMP-9). Levels of MMP-9 in spinal fluid increase in response to breakdowns of the blood-brain barrier.

What does that mean? Well most notably, a “leaky” blood-brain barrier is what allows damaging compounds to enter the brain and trigger inflammation. And brain inflammation is a driving force behind Alzheimer’s-related cognitive decline—leading to greater neuron death and more rapid development of symptoms.

In other words, simply supplementing with resveratrol may be enough to help keep the bad guys out of your brain. And potentially slow down Alzheimer’s disease progression in a significant, measurable way.

Considering how few effective treatments we have against this dreaded diagnosis, this is a very big deal indeed.

It may not be enough to push resveratrol back into my “desert island” rotation. But it’s a fantastic reminder that this is one supplement that has really stood the test of time. I recommend taking 500 mg daily.



Georgetown University Medical Center. “Resveratrol appears to restore blood-brain barrier integrity in Alzheimer’s disease.” ScienceDaily, 27 July 2016.